Disinfectant.



sEs

RICHARD HAER'I'EL, 0F BASEL, SWITZERLAND, ASSIGNOR TO THE FIRM OF F.HOFFMANN LA ROCHE AND COMPANY, OF BASEL, SWITZERLAND.

Patented July 4, 1911.

DISINFECTANT.

996,759. Specification of Letters Patent.

No Drawing.

To all whom it may concern:

Be it known that I,RICHARD HAERTEL, chemist, a subject of the GermanEmperor, residing at Basel, Switzerland, have invented a certain new anduseful Disinfectant, of which the following is a specification.

This invention relates to a disinfectant prepared from chloro-metacresolwhich on the base of numerous experiments is considered the bestdisinfectant among the phenol group. Hitherto the practical utilization,of this compound has been impeded by'its low solubility in water.

I have found that it is possible to obtain preparations, which formclear solutions with water, by adding glycerin and alcohol to a solutionof chloro-metacresol and soap.

The favorable effect of glycerin and alcohol could not be predicted,especially as the ad dition of glycerin alone will not produce thedesired effect. In preparing concentrated solutions of chloro-metacresolthe contents of water of the soap is to be diminished by heating on awater-bath, because by employing the usual potassium soap (containing4.0 to 50 per cent. of water) it is impossible to obtain a higherconcentration than 25 per cent. of chloro-metacresol, giving with waterclear liquids.

The proportions between chloro-metacresol, soap, glycerin and alcoholmay, of course,

be varled within certain limits, and the water contents of the soap canbe varied according to the concentration of the solution, but theproportions shown by the following examples have been found especiallysuitable Example I, a 25 per cent. solution of chlorometacresol: 500grams soft soap (containing 40 per cent. of water) and 250 gramsApplication filed February 1, 1910. Serial No. 541,292.

of chloro-metacresol are melted on a water bath and after cooling, mixedwith 175 grams of alcohol of 96 per cent. and 75 grams of glycerin. Theresult is a clear yellow liquid, which has at 15 C'. a specific gravityof 1.052 and can be mixed wlth alcohol or water in any proportion.

Example II, a 40 per cent. solution of chlorometacresol: 300 grams ofsoft soap (containing 3.5 per cent. of water) and 4.00.0 grams ofchloro-metac esol are melted on a water bath, and after cooling thereare added 250.0 grams of alcohol of 96 per cent. and 50.0 grams ofglycerin. The result is a clear yellow liquid, which has at 15 C. aspecific gravity of 1.050 and gives with water a clear solution.

If the preparation obtained by the present process is distilled withdilute sulfuric acid in a current of aqueous va'por, a distillate isproduced, which on strong cooling or after prolonged standing separatesout crystals of chloro-metacresol. If the first distillate is mixed withseveral drops of benzoyl-chlorid and heated with caustic soda solution,an aromatical odor of benzoic ether is produced (thus indicating thepresence of alcohol).

What I claim is A disinfecting composition consisting ofchloro-metacresol, soap, glycerin, alcohol and water, substantially asdescribed.

In testimony whereof I have hereunto set my hand in presence of twosubscribing witnesses.

Witnesses GEO. Gmrono, ARNOLD ZUBER.

